KIF3A accelerates KIF3C within the kinesin-2 heterodimer to generate symmetrical phosphate release rates for each processive step

Heterodimeric KIF3AC is a mammalian kinesin-2 that is highly expressed in the central nervous system and associated with vesicles in neurons. KIF3AC is an intriguing member of the kinesin-2 family because the intrinsic kinetics of KIF3A and KIF3C when expressed as homodimers and analyzed in vitro ar...

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Detalles Bibliográficos
Autores principales: Quinn, Sean M., Vargason, Troy, Pokhrel, Nilisha, Antony, Edwin, Hahn, Juergen, Gilbert, Susan P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948976/
https://www.ncbi.nlm.nih.gov/pubmed/33144324
http://dx.doi.org/10.1074/jbc.RA120.015272

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948976/
https://www.ncbi.nlm.nih.gov/pubmed/33144324
http://dx.doi.org/10.1074/jbc.RA120.015272

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