Structural comparisons of host and African swine fever virus dUTPases reveal new clues for inhibitor development

African swine fever, caused by the African swine fever virus (ASFV), is among the most significant swine diseases. There are currently no effective treatments against ASFV. ASFV contains a gene encoding a dUTPase (E165R), which is required for viral replication in swine macrophages, making it an att...

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Detalles Bibliográficos
Autores principales: Liang, Rui, Wang, Gang, Zhang, Ding, Ye, Gang, Li, Mengxia, Shi, Yuejun, Shi, Jiale, Chen, Huanchun, Peng, Guiqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948977/
https://www.ncbi.nlm.nih.gov/pubmed/33139328
http://dx.doi.org/10.1074/jbc.RA120.014005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7948977/
https://www.ncbi.nlm.nih.gov/pubmed/33139328
http://dx.doi.org/10.1074/jbc.RA120.014005

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