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Biophysical characterization of the ETV6 PNT domain polymerization interfaces

ETV6 is an E26 transformation specific family transcriptional repressor that self-associates by its PNT domain to facilitate cooperative DNA binding. Chromosomal translocations frequently generate constitutively active oncoproteins with the ETV6 PNT domain fused to the kinase domain of one of many p...

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Detalles Bibliográficos
Autores principales:	Gerak, Chloe A.N., Cho, Sophia Y., Kolesnikov, Maxim, Okon, Mark, Murphy, Michael E.P., Sessions, Richard B., Roberge, Michel, McIntosh, Lawrence P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949025/ https://www.ncbi.nlm.nih.gov/pubmed/33450226 http://dx.doi.org/10.1016/j.jbc.2021.100284

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