The KH domain facilitates the substrate specificity and unwinding processivity of DDX43 helicase

The K-homology (KH) domain is a nucleic acid–binding domain present in many proteins. Recently, we found that the DEAD-box helicase DDX43 contains a KH domain in its N-terminus; however, its function remains unknown. Here, we purified recombinant DDX43 KH domain protein and found that it prefers bin...

Descripción completa

Detalles Bibliográficos
Autores principales: Yadav, Manisha, Singh, Ravi Shankar, Hogan, Daniel, Vidhyasagar, Venkatasubramanian, Yang, Shizhuo, Chung, Ivy Yeuk Wah, Kusalik, Anthony, Dmitriev, Oleg Y., Cygler, Miroslaw, Wu, Yuliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949032/
https://www.ncbi.nlm.nih.gov/pubmed/33199368
http://dx.doi.org/10.1074/jbc.RA120.015824

Ejemplares similares

Ejemplares similares