The allosteric inhibition of glycine transporter 2 by bioactive lipid analgesics is controlled by penetration into a deep lipid cavity

The role of lipids in modulating membrane protein function is an emerging and rapidly growing area of research. The rational design of lipids that target membrane proteins for the treatment of pathological conditions is a novel extension in this field and provides a step forward in our understanding...

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Detalles Bibliográficos
Autores principales: Wilson, Katie A., Mostyn, Shannon N., Frangos, Zachary J., Shimmon, Susan, Rawling, Tristan, Vandenberg, Robert J., O’Mara, Megan L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949037/
https://www.ncbi.nlm.nih.gov/pubmed/33450225
http://dx.doi.org/10.1016/j.jbc.2021.100282

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949037/
https://www.ncbi.nlm.nih.gov/pubmed/33450225
http://dx.doi.org/10.1016/j.jbc.2021.100282

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