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Decreases in different Dnmt3b activities drive distinct development of hematologic malignancies in mice

DNA methylation regulates gene transcription and is involved in various physiological processes in mammals, including development and hematopoiesis. It is catalyzed by DNA methyltransferases including Dnmt1, Dnmt3a, and Dnmt3b. For Dnmt3b, its effects on transcription can result from its own DNA met...

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Detalles Bibliográficos
Autores principales:	Lopusna, Katarina, Nowialis, Pawel, Opavska, Jana, Abraham, Ajay, Riva, Alberto, Haney, Staci L., Opavsky, Rene
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949038/ https://www.ncbi.nlm.nih.gov/pubmed/33450231 http://dx.doi.org/10.1016/j.jbc.2021.100285

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