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TET-mediated 5-methylcytosine oxidation in tRNA promotes translation

Oxidation of 5-methylcytosine (5mC) in DNA by the ten-eleven translocation (TET) family of enzymes is indispensable for gene regulation in mammals. More recently, evidence has emerged to support a biological function for TET-mediated m(5)C oxidation in messenger RNA. Here, we describe a previously u...

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Detalles Bibliográficos
Autores principales: Shen, Hui, Ontiveros, Robert Jordan, Owens, Michael C., Liu, Monica Yun, Ghanty, Uday, Kohli, Rahul M., Liu, Kathy Fange
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949041/
https://www.ncbi.nlm.nih.gov/pubmed/33199375
http://dx.doi.org/10.1074/jbc.RA120.014226

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