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Rod photoreceptor clearance due to misfolded rhodopsin is linked to a DAMP-immune checkpoint switch

Chronic endoplasmic reticulum stress resulting from misfolding of the visual pigment rhodopsin (RHO) can lead to loss of rod photoreceptors, which initiates retinitis pigmentosa, characterized initially by diminished nighttime and peripheral vision. Cone photoreceptors depend on rods for glucose tra...

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Detalles Bibliográficos
Autores principales:	Lee, Sang Joon, Wang, Wei, Jin, Lei, Lu, Xiaoqin, Gao, Lei, Chen, Yao, Liu, Tingting, Emery, Douglas, Vukmanic, Eric, Liu, Yongqing, Kaplan, Henry J., Dean, Douglas C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949052/ https://www.ncbi.nlm.nih.gov/pubmed/33214223 http://dx.doi.org/10.1074/jbc.RA120.016053

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