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The cytoprotective protein MANF promotes neuronal survival independently from its role as a GRP78 cofactor
Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum (ER)-stress–regulated protein exhibiting cytoprotective properties through a poorly understood mechanism in various in vitro and in vivo models of neuronal and non-neuronal damage. Although initially characterized...
Autores principales: | Eesmaa, Ave, Yu, Li-Ying, Göös, Helka, Nõges, Kristofer, Kovaleva, Vera, Hellman, Maarit, Zimmermann, Richard, Jung, Martin, Permi, Perttu, Varjosalo, Markku, Lindholm, Päivi, Saarma, Mart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949057/ https://www.ncbi.nlm.nih.gov/pubmed/33460650 http://dx.doi.org/10.1016/j.jbc.2021.100295 |
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