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Muscle-specific TGR5 overexpression improves glucose clearance in glucose-intolerant mice

TGR5, a G protein–coupled bile acid receptor, is expressed in various tissues and regulates several physiological processes. In the skeletal muscle, TGR5 activation is known to induce muscle hypertrophy; however, the effects on glucose and lipid metabolism are not well understood, despite the fact t...

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Detalles Bibliográficos
Autores principales: Sasaki, Takashi, Watanabe, Yuichi, Kuboyama, Ayane, Oikawa, Akira, Shimizu, Makoto, Yamauchi, Yoshio, Sato, Ryuichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949087/
https://www.ncbi.nlm.nih.gov/pubmed/33262218
http://dx.doi.org/10.1074/jbc.RA120.016203