Using biochemistry and biophysics to extinguish androgen receptor signaling in prostate cancer

Castration resistant prostate cancer (CRPC) continues to be androgen receptor (AR) driven. Inhibition of AR signaling in CRPC could be advanced using state-of-the-art biophysical and biochemical techniques. Structural characterization of AR and its complexes by cryo-electron microscopy would advance...

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Detalles Bibliográficos
Autores principales: Asangani, Irfan, Blair, Ian A., Van Duyne, Gregory, Hilser, Vincent J., Moiseenkova-Bell, Vera, Plymate, Stephen, Sprenger, Cynthia, Wand, A. Joshua, Penning, Trevor M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
JBC Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949100/
https://www.ncbi.nlm.nih.gov/pubmed/33384381
http://dx.doi.org/10.1074/jbc.REV120.012411

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