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Disturbed intramitochondrial phosphatidic acid transport impairs cellular stress signaling

Lipid transfer proteins of the Ups1/PRELID1 family facilitate the transport of phospholipids across the intermembrane space of mitochondria in a lipid-specific manner. Heterodimeric complexes of yeast Ups1/Mdm35 or human PRELID1/TRIAP1 shuttle phosphatidic acid (PA) mainly synthesized in the endopla...

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Detalles Bibliográficos
Autores principales: Eiyama, Akinori, Aaltonen, Mari J., Nolte, Hendrik, Tatsuta, Takashi, Langer, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949116/
https://www.ncbi.nlm.nih.gov/pubmed/33497623
http://dx.doi.org/10.1016/j.jbc.2021.100335

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