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The steroid hormone 20-hydroxyecdysone counteracts insulin signaling via insulin receptor dephosphorylation
The insulin receptor (INSR) binds insulin to promote body growth and maintain normal blood glucose levels. While it is known that steroid hormones such as estrogen and 20-hydroxyecdysone counteract insulin function, the molecular mechanisms responsible for this attenuation remain unclear. In the pre...
Autores principales: | Li, Yan-Li, Yao, You-Xiang, Zhao, Yu-Meng, Di, Yu-Qin, Zhao, Xiao-Fan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949120/ https://www.ncbi.nlm.nih.gov/pubmed/33484713 http://dx.doi.org/10.1016/j.jbc.2021.100318 |
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