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The steroid hormone 20-hydroxyecdysone counteracts insulin signaling via insulin receptor dephosphorylation

The insulin receptor (INSR) binds insulin to promote body growth and maintain normal blood glucose levels. While it is known that steroid hormones such as estrogen and 20-hydroxyecdysone counteract insulin function, the molecular mechanisms responsible for this attenuation remain unclear. In the pre...

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Detalles Bibliográficos
Autores principales: Li, Yan-Li, Yao, You-Xiang, Zhao, Yu-Meng, Di, Yu-Qin, Zhao, Xiao-Fan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949120/
https://www.ncbi.nlm.nih.gov/pubmed/33484713
http://dx.doi.org/10.1016/j.jbc.2021.100318

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