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Maturation, inactivation, and recovery mechanisms of soluble guanylyl cyclase

Soluble guanylate cyclase (sGC) is a heme-containing heterodimeric enzyme that generates many molecules of cGMP in response to its ligand nitric oxide (NO); sGC thereby acts as an amplifier in NO-driven biological signaling cascades. Because sGC helps regulate the cardiovascular, neuronal, and gastr...

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Detalles Bibliográficos
Autores principales: Stuehr, Dennis J., Misra, Saurav, Dai, Yue, Ghosh, Arnab
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949132/
https://www.ncbi.nlm.nih.gov/pubmed/33508317
http://dx.doi.org/10.1016/j.jbc.2021.100336

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