Cargando…
Maturation, inactivation, and recovery mechanisms of soluble guanylyl cyclase
Soluble guanylate cyclase (sGC) is a heme-containing heterodimeric enzyme that generates many molecules of cGMP in response to its ligand nitric oxide (NO); sGC thereby acts as an amplifier in NO-driven biological signaling cascades. Because sGC helps regulate the cardiovascular, neuronal, and gastr...
Autores principales: | Stuehr, Dennis J., Misra, Saurav, Dai, Yue, Ghosh, Arnab |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949132/ https://www.ncbi.nlm.nih.gov/pubmed/33508317 http://dx.doi.org/10.1016/j.jbc.2021.100336 |
Ejemplares similares
-
An inherent dysfunction in soluble guanylyl cyclase is present in the airway of severe asthmatics and is associated with aberrant redox enzyme expression and compromised NO-cGMP signaling
por: Ghosh, Arnab, et al.
Publicado: (2020) -
Nucleotidyl cyclase activity of recombinant soluble guanylyl cyclase
por: Rauch, Kerstin, et al.
Publicado: (2009) -
Regulation of soluble guanylyl cyclase by phosphorylation
por: Zhou, Zongmin, et al.
Publicado: (2009) -
Regulation of soluble guanylyl cyclase by phosphorylation
por: Zhou, Zongmin, et al.
Publicado: (2009) -
Targeting Soluble Guanylyl Cyclase during Ischemia and Reperfusion
por: Mace, Eric H., et al.
Publicado: (2023)