Cargando…

How bacteria block their own biofilms

Bacterial biofilms are surface-associated multicellular communities that are highly resistant to removal. Scheffler et al. discovered that Pseudomonas aeruginosa secretes a small molecule that inhibits other P. aeruginosa cells from adsorbing to surfaces by interfering with type IV pili dynamics. Th...

Descripción completa

Detalles Bibliográficos
Autores principales: Delerue, Thomas, Ramamurthi, Kumaran S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949149/
https://www.ncbi.nlm.nih.gov/pubmed/33839681
http://dx.doi.org/10.1016/j.jbc.2021.100392
_version_ 1783663501211860992
author Delerue, Thomas
Ramamurthi, Kumaran S.
author_facet Delerue, Thomas
Ramamurthi, Kumaran S.
author_sort Delerue, Thomas
collection PubMed
description Bacterial biofilms are surface-associated multicellular communities that are highly resistant to removal. Scheffler et al. discovered that Pseudomonas aeruginosa secretes a small molecule that inhibits other P. aeruginosa cells from adsorbing to surfaces by interfering with type IV pili dynamics. The inhibition of cell adsorption could present a method to prevent biofilm formation on sensitive surfaces in hospitals and industry.
format Online
Article
Text
id pubmed-7949149
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher American Society for Biochemistry and Molecular Biology
record_format MEDLINE/PubMed
spelling pubmed-79491492021-03-19 How bacteria block their own biofilms Delerue, Thomas Ramamurthi, Kumaran S. J Biol Chem Editors' Pick Highlight Bacterial biofilms are surface-associated multicellular communities that are highly resistant to removal. Scheffler et al. discovered that Pseudomonas aeruginosa secretes a small molecule that inhibits other P. aeruginosa cells from adsorbing to surfaces by interfering with type IV pili dynamics. The inhibition of cell adsorption could present a method to prevent biofilm formation on sensitive surfaces in hospitals and industry. American Society for Biochemistry and Molecular Biology 2021-03-04 /pmc/articles/PMC7949149/ /pubmed/33839681 http://dx.doi.org/10.1016/j.jbc.2021.100392 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Editors' Pick Highlight
Delerue, Thomas
Ramamurthi, Kumaran S.
How bacteria block their own biofilms
title How bacteria block their own biofilms
title_full How bacteria block their own biofilms
title_fullStr How bacteria block their own biofilms
title_full_unstemmed How bacteria block their own biofilms
title_short How bacteria block their own biofilms
title_sort how bacteria block their own biofilms
topic Editors' Pick Highlight
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949149/
https://www.ncbi.nlm.nih.gov/pubmed/33839681
http://dx.doi.org/10.1016/j.jbc.2021.100392
work_keys_str_mv AT deleruethomas howbacteriablocktheirownbiofilms
AT ramamurthikumarans howbacteriablocktheirownbiofilms