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How bacteria block their own biofilms
Bacterial biofilms are surface-associated multicellular communities that are highly resistant to removal. Scheffler et al. discovered that Pseudomonas aeruginosa secretes a small molecule that inhibits other P. aeruginosa cells from adsorbing to surfaces by interfering with type IV pili dynamics. Th...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949149/ https://www.ncbi.nlm.nih.gov/pubmed/33839681 http://dx.doi.org/10.1016/j.jbc.2021.100392 |
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author | Delerue, Thomas Ramamurthi, Kumaran S. |
author_facet | Delerue, Thomas Ramamurthi, Kumaran S. |
author_sort | Delerue, Thomas |
collection | PubMed |
description | Bacterial biofilms are surface-associated multicellular communities that are highly resistant to removal. Scheffler et al. discovered that Pseudomonas aeruginosa secretes a small molecule that inhibits other P. aeruginosa cells from adsorbing to surfaces by interfering with type IV pili dynamics. The inhibition of cell adsorption could present a method to prevent biofilm formation on sensitive surfaces in hospitals and industry. |
format | Online Article Text |
id | pubmed-7949149 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | American Society for Biochemistry and Molecular Biology |
record_format | MEDLINE/PubMed |
spelling | pubmed-79491492021-03-19 How bacteria block their own biofilms Delerue, Thomas Ramamurthi, Kumaran S. J Biol Chem Editors' Pick Highlight Bacterial biofilms are surface-associated multicellular communities that are highly resistant to removal. Scheffler et al. discovered that Pseudomonas aeruginosa secretes a small molecule that inhibits other P. aeruginosa cells from adsorbing to surfaces by interfering with type IV pili dynamics. The inhibition of cell adsorption could present a method to prevent biofilm formation on sensitive surfaces in hospitals and industry. American Society for Biochemistry and Molecular Biology 2021-03-04 /pmc/articles/PMC7949149/ /pubmed/33839681 http://dx.doi.org/10.1016/j.jbc.2021.100392 Text en https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Editors' Pick Highlight Delerue, Thomas Ramamurthi, Kumaran S. How bacteria block their own biofilms |
title | How bacteria block their own biofilms |
title_full | How bacteria block their own biofilms |
title_fullStr | How bacteria block their own biofilms |
title_full_unstemmed | How bacteria block their own biofilms |
title_short | How bacteria block their own biofilms |
title_sort | how bacteria block their own biofilms |
topic | Editors' Pick Highlight |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949149/ https://www.ncbi.nlm.nih.gov/pubmed/33839681 http://dx.doi.org/10.1016/j.jbc.2021.100392 |
work_keys_str_mv | AT deleruethomas howbacteriablocktheirownbiofilms AT ramamurthikumarans howbacteriablocktheirownbiofilms |