Cargando…

Motifs of the C-terminal domain of MCM9 direct localization to sites of mitomycin-C damage for RAD51 recruitment

The MCM8/9 complex is implicated in aiding fork progression and facilitating homologous recombination (HR) in response to several DNA damage agents. MCM9 itself is an outlier within the MCM family containing a long C-terminal extension (CTE) comprising 42% of the total length, but with no known func...

Descripción completa

Detalles Bibliográficos
Autores principales: McKinzey, David R., Gomathinayagam, Shivasankari, Griffin, Wezley C., Klinzing, Kathleen N., Jeffries, Elizabeth P., Rajkovic, Aleksandar, Trakselis, Michael A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949153/
https://www.ncbi.nlm.nih.gov/pubmed/33539926
http://dx.doi.org/10.1016/j.jbc.2021.100355