Suppression of the NTS-CPS1 regulatory axis by AFF1 in lung adenocarcinoma cells

Upregulation of the neuropeptide neurotensin (NTS) in a subgroup of lung cancers has been linked to poor prognosis. However, the regulatory pathway centered on NTS in lung cancer remains unclear. Here we identified the NTS-specific enhancer in lung adenocarcinoma cells. The AF4/FMR2 (AFF) family pro...

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Detalles Bibliográficos
Autores principales: Yue, Junjie, Dai, Qian, Hao, Shaohua, Zhu, Shiqi, Liu, Xiaoxu, Tang, Zhiqun, Li, Meng, Fang, Haitong, Lin, Chengqi, Luo, Zhuojuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949158/
https://www.ncbi.nlm.nih.gov/pubmed/33493519
http://dx.doi.org/10.1016/j.jbc.2021.100319

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