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Hepatic LDL receptor-related protein-1 deficiency alters mitochondrial dynamics through phosphatidylinositol 4,5-bisphosphate reduction

The LDL receptor-related protein 1 (LRP1) is a multifunctional transmembrane protein with endocytosis and signal transduction functions. Previous studies have shown that hepatic LRP1 deficiency exacerbates diet-induced steatohepatitis and insulin resistance via mechanisms related to increased lysoso...

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Detalles Bibliográficos
Autores principales:	Chinnarasu, Sivaprakasam, Alogaili, Fawzi, Bove, Kevin E., Jaeschke, Anja, Hui, David Y.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949165/ https://www.ncbi.nlm.nih.gov/pubmed/33548224 http://dx.doi.org/10.1016/j.jbc.2021.100370

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