Cargando…

Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore

Ischaemic diabetic heel ulcers are difficult to treat and prognosis is often guarded. The aim was to document our outcome of treating heel ulcers following revascularization in a predominantly diabetic Asian cohort presenting with chronic limb threatening ischaemia from Singapore. Retrospective coho...

Descripción completa

Detalles Bibliográficos
Autores principales: Linn, Yun Le, Chan, Sze Ling, Soon, Shereen Xue Yun, Yap, Charyl Jia Qi, Lim, Mervin Nathan Han Hui, Lee, Qing Wei Shaun, Chong, Tze Tec, Tang, Tjun Yip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949176/
https://www.ncbi.nlm.nih.gov/pubmed/32840061
http://dx.doi.org/10.1111/iwj.13493
_version_ 1783663504973103104
author Linn, Yun Le
Chan, Sze Ling
Soon, Shereen Xue Yun
Yap, Charyl Jia Qi
Lim, Mervin Nathan Han Hui
Lee, Qing Wei Shaun
Chong, Tze Tec
Tang, Tjun Yip
author_facet Linn, Yun Le
Chan, Sze Ling
Soon, Shereen Xue Yun
Yap, Charyl Jia Qi
Lim, Mervin Nathan Han Hui
Lee, Qing Wei Shaun
Chong, Tze Tec
Tang, Tjun Yip
author_sort Linn, Yun Le
collection PubMed
description Ischaemic diabetic heel ulcers are difficult to treat and prognosis is often guarded. The aim was to document our outcome of treating heel ulcers following revascularization in a predominantly diabetic Asian cohort presenting with chronic limb threatening ischaemia from Singapore. Retrospective cohort study (n = 66, 66 limbs) over a 5‐year period. Data were collected from hospital electronic health records. Outcomes included time to healing, amputation free survival (AFS), and mortality. Minimum follow‐up period was 6 months. Multivariate regression analysis was performed to look for factors associated with poor outcome. Mean age was 67.4 ± 8.8 years. 62/66 (93.9%) were diabetics. Mean wound size at presentation was 3.6 ± 2.3 cm. Mean Wound, Ischaemia, Foot Infection (WIFI) score was 5 ± 1.6. 12/66 (18%) patients had a patent posterior tibial artery pre‐operatively. Straight line flow was restored in only 31/66 (46.9) patients but 47/66 (71.2%) had successful limb salvage. Median time to wound healing was 90.0 (IQR 60‐180) days. A median of 1 (IQR 0‐2) wound debridement was required. Patients who underwent negative pressure dressing (23/66; 34.8%) required a median of 26 (IQR 13‐33) cycles to achieve healing. Amputation free survival (AFS) was 72% and 68% at 6‐ and 12‐months, respectively. Mortality rate was 16.7% and 19.7% at 6‐ and 12‐months, respectively. Low albumin level and initial Rutherford class were independent predictors of worse 6‐month AFS. Outcomes of heel ulcers post revascularisation may not be as poor as previously described. Persistent attention to wound care with multidisciplinary effort is needed for optimal healing.
format Online
Article
Text
id pubmed-7949176
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Blackwell Publishing Ltd
record_format MEDLINE/PubMed
spelling pubmed-79491762021-07-02 Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore Linn, Yun Le Chan, Sze Ling Soon, Shereen Xue Yun Yap, Charyl Jia Qi Lim, Mervin Nathan Han Hui Lee, Qing Wei Shaun Chong, Tze Tec Tang, Tjun Yip Int Wound J Original Articles Ischaemic diabetic heel ulcers are difficult to treat and prognosis is often guarded. The aim was to document our outcome of treating heel ulcers following revascularization in a predominantly diabetic Asian cohort presenting with chronic limb threatening ischaemia from Singapore. Retrospective cohort study (n = 66, 66 limbs) over a 5‐year period. Data were collected from hospital electronic health records. Outcomes included time to healing, amputation free survival (AFS), and mortality. Minimum follow‐up period was 6 months. Multivariate regression analysis was performed to look for factors associated with poor outcome. Mean age was 67.4 ± 8.8 years. 62/66 (93.9%) were diabetics. Mean wound size at presentation was 3.6 ± 2.3 cm. Mean Wound, Ischaemia, Foot Infection (WIFI) score was 5 ± 1.6. 12/66 (18%) patients had a patent posterior tibial artery pre‐operatively. Straight line flow was restored in only 31/66 (46.9) patients but 47/66 (71.2%) had successful limb salvage. Median time to wound healing was 90.0 (IQR 60‐180) days. A median of 1 (IQR 0‐2) wound debridement was required. Patients who underwent negative pressure dressing (23/66; 34.8%) required a median of 26 (IQR 13‐33) cycles to achieve healing. Amputation free survival (AFS) was 72% and 68% at 6‐ and 12‐months, respectively. Mortality rate was 16.7% and 19.7% at 6‐ and 12‐months, respectively. Low albumin level and initial Rutherford class were independent predictors of worse 6‐month AFS. Outcomes of heel ulcers post revascularisation may not be as poor as previously described. Persistent attention to wound care with multidisciplinary effort is needed for optimal healing. Blackwell Publishing Ltd 2020-08-24 /pmc/articles/PMC7949176/ /pubmed/32840061 http://dx.doi.org/10.1111/iwj.13493 Text en © 2020 The Authors. International Wound Journal published by Medicalhelplines.com Inc and John Wiley & Sons Ltd. This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited and is not used for commercial purposes.
spellingShingle Original Articles
Linn, Yun Le
Chan, Sze Ling
Soon, Shereen Xue Yun
Yap, Charyl Jia Qi
Lim, Mervin Nathan Han Hui
Lee, Qing Wei Shaun
Chong, Tze Tec
Tang, Tjun Yip
Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore
title Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore
title_full Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore
title_fullStr Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore
title_full_unstemmed Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore
title_short Heal or no heel: Outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic Asian Cohort in Singapore
title_sort heal or no heel: outcomes of ischaemic heel ulcers following lower limb revascularization from a multi‐ethnic asian cohort in singapore
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7949176/
https://www.ncbi.nlm.nih.gov/pubmed/32840061
http://dx.doi.org/10.1111/iwj.13493
work_keys_str_mv AT linnyunle healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore
AT chanszeling healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore
AT soonshereenxueyun healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore
AT yapcharyljiaqi healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore
AT limmervinnathanhanhui healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore
AT leeqingweishaun healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore
AT chongtzetec healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore
AT tangtjunyip healornoheeloutcomesofischaemicheelulcersfollowinglowerlimbrevascularizationfromamultiethnicasiancohortinsingapore