SIRT6 enhances telomerase activity to protect against DNA damage and senescence in hypertrophic ligamentum flavum cells from lumbar spinal stenosis patients

Lumbar spinal stenosis (LSS) is a condition wherein patients exhibit age-related fibrosis, elastin-to-collagen ratio reductions, and ligamentum flavum hypertrophy. This study was designed to assess the relationship between SIRT6 and telomerase activity in hypertrophic ligamentum flavum (LFH) cells f...

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Detalles Bibliográficos
Autores principales: Chen, Jianwei, Liu, Zude, Wang, Hantao, Qian, Lie, Li, Zhanchun, Song, Qingxin, Zhong, Guibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950242/
https://www.ncbi.nlm.nih.gov/pubmed/33568575
http://dx.doi.org/10.18632/aging.202536

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950242/
https://www.ncbi.nlm.nih.gov/pubmed/33568575
http://dx.doi.org/10.18632/aging.202536

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