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Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway

The Notch1-mediated inflammatory response participates in the development of abdominal aortic aneurysm (AAA). The vascular endogenous bioactive peptide intermedin (IMD) plays an important role in maintaining vascular homeostasis. However, whether IMD inhibits AAA by inhibiting Notch1-mediated inflam...

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Detalles Bibliográficos
Autores principales: Ni, Xian-Qiang, Zhang, Ya-Rong, Jia, Li-Xin, Lu, Wei-Wei, Zhu, Qing, Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Liu, Xin, Yu, Yan-Rong, Jia, Mo-Zhi, Ning, Zhong-Ping, Du, Jie, Tang, Chao-Shu, Qi, Yong-Fen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950288/
https://www.ncbi.nlm.nih.gov/pubmed/33535178
http://dx.doi.org/10.18632/aging.202436

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