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Inhibition of Notch1-mediated inflammation by intermedin protects against abdominal aortic aneurysm via PI3K/Akt signaling pathway
The Notch1-mediated inflammatory response participates in the development of abdominal aortic aneurysm (AAA). The vascular endogenous bioactive peptide intermedin (IMD) plays an important role in maintaining vascular homeostasis. However, whether IMD inhibits AAA by inhibiting Notch1-mediated inflam...
Autores principales: | Ni, Xian-Qiang, Zhang, Ya-Rong, Jia, Li-Xin, Lu, Wei-Wei, Zhu, Qing, Ren, Jin-Ling, Chen, Yao, Zhang, Lin-Shuang, Liu, Xin, Yu, Yan-Rong, Jia, Mo-Zhi, Ning, Zhong-Ping, Du, Jie, Tang, Chao-Shu, Qi, Yong-Fen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950288/ https://www.ncbi.nlm.nih.gov/pubmed/33535178 http://dx.doi.org/10.18632/aging.202436 |
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