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Synergistic inflammatory signaling by cGAS may be involved in the development of atherosclerosis

Inappropriate activation or overactivation of cyclic GMP-AMP synthase (cGAS) by double-stranded deoxyribonucleic acid (dsDNA) initiates a regulatory signaling cascade triggering a variety of inflammatory responses, which are a great threat to human health. This study focused on identifying the role...

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Detalles Bibliográficos
Autores principales: Lu, Guan-Feng, Chen, Sheng-Cai, Xia, Yuan-Peng, Ye, Zi-Ming, Cao, Fei, Hu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950297/
https://www.ncbi.nlm.nih.gov/pubmed/33589571
http://dx.doi.org/10.18632/aging.202491