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Cross-linking and modification of fibronectin by peroxynitrous acid: Mapping and quantification of damage provides a new model for domain interactions

Fibronectin (FN) is an abundant glycoprotein found in plasma and the extracellular matrix (ECM). It is present at high concentrations at sites of tissue damage, where it is exposed to oxidants generated by activated leukocytes, including peroxynitrous acid (ONOOH) formed from nitric oxide (from indu...

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Detalles Bibliográficos
Autores principales: Mariotti, Michele, Rogowska-Wrzesinska, Adelina, Hägglund, Per, Davies, Michael J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950325/
https://www.ncbi.nlm.nih.gov/pubmed/33539924
http://dx.doi.org/10.1016/j.jbc.2021.100360