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Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds
Non healing wounds present a significant social and economic burden. Chronic non healing wounds are estimated to affect as many as 1–2% of individuals during their lifetime, and account for billions of dollars of expense annually on both a national and global basis. Our purpose is to describe the us...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950830/ https://www.ncbi.nlm.nih.gov/pubmed/23409746 http://dx.doi.org/10.1111/iwj.12035 |
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author | Sheikh, Emran S Sheikh, Ednan S Fetterolf, Donald E |
author_facet | Sheikh, Emran S Sheikh, Ednan S Fetterolf, Donald E |
author_sort | Sheikh, Emran S |
collection | PubMed |
description | Non healing wounds present a significant social and economic burden. Chronic non healing wounds are estimated to affect as many as 1–2% of individuals during their lifetime, and account for billions of dollars of expense annually on both a national and global basis. Our purpose is to describe the use of a novel dehydrated amniotic membrane allograft (EpiFix (®); MiMedx Group, Inc., Kennesaw, GA) for the treatment of chronic non healing wounds. We describe the results of EpiFix treatment in four patients who had not achieved wound closure with both conservative and advanced measures, and had been referred for a definitive plastic surgery procedure. Healing was observed in a variety of wounds with one to three applications of the dehydrated amniotic membrane material. The material was well tolerated by patients. Healed wounds did not recur in long‐term follow‐up. Further investigation of the use of dehydrated amniotic membrane in broader application to various types of dermal wounds should be considered. |
format | Online Article Text |
id | pubmed-7950830 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-79508302021-07-02 Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds Sheikh, Emran S Sheikh, Ednan S Fetterolf, Donald E Int Wound J Original Articles Non healing wounds present a significant social and economic burden. Chronic non healing wounds are estimated to affect as many as 1–2% of individuals during their lifetime, and account for billions of dollars of expense annually on both a national and global basis. Our purpose is to describe the use of a novel dehydrated amniotic membrane allograft (EpiFix (®); MiMedx Group, Inc., Kennesaw, GA) for the treatment of chronic non healing wounds. We describe the results of EpiFix treatment in four patients who had not achieved wound closure with both conservative and advanced measures, and had been referred for a definitive plastic surgery procedure. Healing was observed in a variety of wounds with one to three applications of the dehydrated amniotic membrane material. The material was well tolerated by patients. Healed wounds did not recur in long‐term follow‐up. Further investigation of the use of dehydrated amniotic membrane in broader application to various types of dermal wounds should be considered. Blackwell Publishing Ltd 2013-02-15 /pmc/articles/PMC7950830/ /pubmed/23409746 http://dx.doi.org/10.1111/iwj.12035 Text en © 2013 The Authors. International Wound Journal © 2013 Medicalhelplines.com Inc and John Wiley & Sons Ltd Open access. |
spellingShingle | Original Articles Sheikh, Emran S Sheikh, Ednan S Fetterolf, Donald E Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds |
title | Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds |
title_full | Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds |
title_fullStr | Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds |
title_full_unstemmed | Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds |
title_short | Use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds |
title_sort | use of dehydrated human amniotic membrane allografts to promote healing in patients with refractory non healing wounds |
topic | Original Articles |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7950830/ https://www.ncbi.nlm.nih.gov/pubmed/23409746 http://dx.doi.org/10.1111/iwj.12035 |
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