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Peripheral synucleinopathy in Parkinson disease with LRRK2 G2385R variants
OBJECTIVE: Recent studies demonstrated cutaneous phosphorylated α synuclein (p‐syn) deposition in idiopathic and some monogenetic Parkinson disease (PD) patients, suggesting synucleinopathy identical to that in the brain. Although the LRRK2 Gly2385Arg (G2385R) variant is a common PD risk factor in t...
Autores principales: | Yang, Jing, Wang, Hao, Yuan, Yanpeng, Fan, Shiheng, Li, Lanjun, Jiang, Chenyang, Mao, Chengyuan, Shi, Changhe, Xu, Yuming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951097/ https://www.ncbi.nlm.nih.gov/pubmed/33527742 http://dx.doi.org/10.1002/acn3.51301 |
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