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Peripheral synucleinopathy in Parkinson disease with LRRK2 G2385R variants

OBJECTIVE: Recent studies demonstrated cutaneous phosphorylated α synuclein (p‐syn) deposition in idiopathic and some monogenetic Parkinson disease (PD) patients, suggesting synucleinopathy identical to that in the brain. Although the LRRK2 Gly2385Arg (G2385R) variant is a common PD risk factor in t...

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Detalles Bibliográficos
Autores principales: Yang, Jing, Wang, Hao, Yuan, Yanpeng, Fan, Shiheng, Li, Lanjun, Jiang, Chenyang, Mao, Chengyuan, Shi, Changhe, Xu, Yuming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951097/
https://www.ncbi.nlm.nih.gov/pubmed/33527742
http://dx.doi.org/10.1002/acn3.51301

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