CSF parvalbumin levels reflect interneuron loss linked with cortical pathology in multiple sclerosis

INTRODUCTION AND METHODS: In order to verify whether parvalbumin (PVALB), a protein specifically expressed by GABAergic interneurons, could be a MS‐specific marker of grey matter neurodegeneration, we performed neuropathology/molecular analysis of PVALB expression in motor cortex of 40 post‐mortem p...

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Detalles Bibliográficos
Autores principales: Magliozzi, Roberta, Pitteri, Marco, Ziccardi, Stefano, Pisani, Anna Isabella, Montibeller, Luigi, Marastoni, Damiano, Rossi, Stefania, Mazziotti, Valentina, Guandalini, Maddalena, Dapor, Caterina, Schiavi, Gianmarco, Tamanti, Agnese, Nicholas, Richard, Reynolds, Richard, Calabrese, Massimiliano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951111/
https://www.ncbi.nlm.nih.gov/pubmed/33484486
http://dx.doi.org/10.1002/acn3.51298

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