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Human genetic admixture
Throughout human history, large-scale migrations have facilitated the formation of populations with ancestry from multiple previously separated populations. This process leads to subsequent shuffling of genetic ancestry through recombination, producing variation in ancestry between populations, amon...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951803/ https://www.ncbi.nlm.nih.gov/pubmed/33705374 http://dx.doi.org/10.1371/journal.pgen.1009374 |
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author | Korunes, Katharine L. Goldberg, Amy |
author_facet | Korunes, Katharine L. Goldberg, Amy |
author_sort | Korunes, Katharine L. |
collection | PubMed |
description | Throughout human history, large-scale migrations have facilitated the formation of populations with ancestry from multiple previously separated populations. This process leads to subsequent shuffling of genetic ancestry through recombination, producing variation in ancestry between populations, among individuals in a population, and along the genome within an individual. Recent methodological and empirical developments have elucidated the genomic signatures of this admixture process, bringing previously understudied admixed populations to the forefront of population and medical genetics. Under this theme, we present a collection of recent PLOS Genetics publications that exemplify recent progress in human genetic admixture studies, and we discuss potential areas for future work. |
format | Online Article Text |
id | pubmed-7951803 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-79518032021-03-22 Human genetic admixture Korunes, Katharine L. Goldberg, Amy PLoS Genet Review Throughout human history, large-scale migrations have facilitated the formation of populations with ancestry from multiple previously separated populations. This process leads to subsequent shuffling of genetic ancestry through recombination, producing variation in ancestry between populations, among individuals in a population, and along the genome within an individual. Recent methodological and empirical developments have elucidated the genomic signatures of this admixture process, bringing previously understudied admixed populations to the forefront of population and medical genetics. Under this theme, we present a collection of recent PLOS Genetics publications that exemplify recent progress in human genetic admixture studies, and we discuss potential areas for future work. Public Library of Science 2021-03-11 /pmc/articles/PMC7951803/ /pubmed/33705374 http://dx.doi.org/10.1371/journal.pgen.1009374 Text en © 2021 Korunes, Goldberg http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Review Korunes, Katharine L. Goldberg, Amy Human genetic admixture |
title | Human genetic admixture |
title_full | Human genetic admixture |
title_fullStr | Human genetic admixture |
title_full_unstemmed | Human genetic admixture |
title_short | Human genetic admixture |
title_sort | human genetic admixture |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951803/ https://www.ncbi.nlm.nih.gov/pubmed/33705374 http://dx.doi.org/10.1371/journal.pgen.1009374 |
work_keys_str_mv | AT koruneskatharinel humangeneticadmixture AT goldbergamy humangeneticadmixture |