IGF2BP1 is a targetable SRC/MAPK-dependent driver of invasive growth in ovarian cancer

Epithelial-to-mesenchymal transition (EMT) is a hallmark of aggressive, mesenchymal-like high-grade serous ovarian carcinoma (HGSOC). The SRC kinase is a key driver of cancer-associated EMT promoting adherens junction (AJ) disassembly by phosphorylation-driven internalization and degradation of AJ p...

Descripción completa

Detalles Bibliográficos
Autores principales: Bley, Nadine, Schott, Annekatrin, Müller, Simon, Misiak, Danny, Lederer, Marcell, Fuchs, Tommy, Aßmann, Chris, Glaß, Markus, Ihling, Christian, Sinz, Andrea, Pazaitis, Nikolaos, Wickenhauser, Claudia, Vetter, Martina, Ungurs, Olga, Strauss, Hans-Georg, Thomssen, Christoph, Hüttelmaier, Stefan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951963/
https://www.ncbi.nlm.nih.gov/pubmed/32876513
http://dx.doi.org/10.1080/15476286.2020.1812894

Ejemplares similares

Ejemplares similares