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Success of prophylactic antiviral therapy for SARS-CoV-2: Predicted critical efficacies and impact of different drug-specific mechanisms of action
Repurposed drugs that are safe and immediately available constitute a first line of defense against new viral infections. Despite limited antiviral activity against SARS-CoV-2, several drugs are being tested as medication or as prophylaxis to prevent infection. Using a stochastic model of early phas...
Autores principales: | Czuppon, Peter, Débarre, Florence, Gonçalves, Antonio, Tenaillon, Olivier, Perelson, Alan S., Guedj, Jérémie, Blanquart, François |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951973/ https://www.ncbi.nlm.nih.gov/pubmed/33647008 http://dx.doi.org/10.1371/journal.pcbi.1008752 |
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