Metabolism in Invariant Natural Killer T Cells: An Overview

Cellular metabolism is critical for generating energy and macromolecules for cell growth and survival. In recent years, the importance of metabolism in mediating T cell differentiation, proliferation, and function has been a hot topic of investigation. However, very little is known about metabolic r...

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Detalles Bibliográficos
Autores principales: Yarosz, Emily L., Chang, Cheong-Hee, Kumar, Ajay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7951988/
https://www.ncbi.nlm.nih.gov/pubmed/33717605
http://dx.doi.org/10.20900/immunometab20210010
Descripción
Sumario:Cellular metabolism is critical for generating energy and macromolecules for cell growth and survival. In recent years, the importance of metabolism in mediating T cell differentiation, proliferation, and function has been a hot topic of investigation. However, very little is known about metabolic regulation in invariant natural killer T (iNKT) cells. In this viewpoint, we will discuss what is currently known about immunometabolism in iNKT cells and how these findings relate to CD4 T cells.

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