Acute Type A Dissection during Pregnancy with Marfan's Syndrome

Background  Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular syste...

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Autores principales: Heim, Christian, Müller, Philipp P., Weyand, Michael, Harig, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Georg Thieme Verlag KG 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952195/
https://www.ncbi.nlm.nih.gov/pubmed/33717827
http://dx.doi.org/10.1055/s-0040-1722705
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author Heim, Christian
Müller, Philipp P.
Weyand, Michael
Harig, Frank
author_facet Heim, Christian
Müller, Philipp P.
Weyand, Michael
Harig, Frank
author_sort Heim, Christian
collection PubMed
description Background  Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular system. Case Description  We present a 39-year-old woman that suffered from an acute aortic dissection in week 33 of her third pregnancy who urgently required lifesaving surgery. Three-dimensional reconstruction of computed tomography scan was performed with unborn child in utero. Conclusion  Monitoring of patients with suspected or confirmed MFS appears essential and interdisciplinary treatment and prevention strategies are required.
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spelling pubmed-79521952021-03-12 Acute Type A Dissection during Pregnancy with Marfan's Syndrome Heim, Christian Müller, Philipp P. Weyand, Michael Harig, Frank Thorac Cardiovasc Surg Rep Background  Marfan's syndrome (MFS) is a connective tissue disorder, caused by a mutation in the FBN-1 gene and affecting multiple organ systems including the vascular system. During pregnancy, women with MFS have an increased risk of aortic dissection due to changes in the cardiovascular system. Case Description  We present a 39-year-old woman that suffered from an acute aortic dissection in week 33 of her third pregnancy who urgently required lifesaving surgery. Three-dimensional reconstruction of computed tomography scan was performed with unborn child in utero. Conclusion  Monitoring of patients with suspected or confirmed MFS appears essential and interdisciplinary treatment and prevention strategies are required. Georg Thieme Verlag KG 2021-01 2021-03-11 /pmc/articles/PMC7952195/ /pubmed/33717827 http://dx.doi.org/10.1055/s-0040-1722705 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Heim, Christian
Müller, Philipp P.
Weyand, Michael
Harig, Frank
Acute Type A Dissection during Pregnancy with Marfan's Syndrome
title Acute Type A Dissection during Pregnancy with Marfan's Syndrome
title_full Acute Type A Dissection during Pregnancy with Marfan's Syndrome
title_fullStr Acute Type A Dissection during Pregnancy with Marfan's Syndrome
title_full_unstemmed Acute Type A Dissection during Pregnancy with Marfan's Syndrome
title_short Acute Type A Dissection during Pregnancy with Marfan's Syndrome
title_sort acute type a dissection during pregnancy with marfan's syndrome
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952195/
https://www.ncbi.nlm.nih.gov/pubmed/33717827
http://dx.doi.org/10.1055/s-0040-1722705
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