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Clinical Characteristics of Patients With Pancreatic Cancer and Pathogenic ATM Alterations

The Ataxia-Telangiesctasia, mutated (ATM) gene is involved in a number of DNA damage repair pathways and confers an increased risk for pancreatic ductal adenocarcinoma (PDAC). In this retrospective study, we identified and profiled 22 patients with PDAC and a known somatic or germline pathogenic ATM...

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Detalles Bibliográficos
Autores principales: Hannan, Zain, Yu, Shun, Domchek, Susan, Mamtani, Ronac, Reiss, Kim A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952223/
https://www.ncbi.nlm.nih.gov/pubmed/33733050
http://dx.doi.org/10.1093/jncics/pkaa121