Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders

Accumulation of the protein α-synuclein into insoluble intracellular deposits termed Lewy bodies (LBs) is the characteristic neuropathological feature of LB diseases, such as Parkinson’s disease (PD), Parkinson’s disease dementia (PDD) and dementia with LB (DLB). α-Synuclein aggregation is thought t...

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Detalles Bibliográficos
Autores principales: Erskine, Daniel, Koss, David, Korolchuk, Viktor I., Outeiro, Tiago F., Attems, Johannes, McKeith, Ian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952289/
https://www.ncbi.nlm.nih.gov/pubmed/33515275
http://dx.doi.org/10.1007/s00401-021-02266-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952289/
https://www.ncbi.nlm.nih.gov/pubmed/33515275
http://dx.doi.org/10.1007/s00401-021-02266-7

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