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Lipids, lysosomes and mitochondria: insights into Lewy body formation from rare monogenic disorders
Accumulation of the protein α-synuclein into insoluble intracellular deposits termed Lewy bodies (LBs) is the characteristic neuropathological feature of LB diseases, such as Parkinson’s disease (PD), Parkinson’s disease dementia (PDD) and dementia with LB (DLB). α-Synuclein aggregation is thought t...
Autores principales: | Erskine, Daniel, Koss, David, Korolchuk, Viktor I., Outeiro, Tiago F., Attems, Johannes, McKeith, Ian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952289/ https://www.ncbi.nlm.nih.gov/pubmed/33515275 http://dx.doi.org/10.1007/s00401-021-02266-7 |
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