Cargando…
Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia
Contagious bovine pleuropneumonia (CBPP) is an infectious and highly contagious respiratory disease of cattle and water buffalo, which is caused by the Mycoplasma mycoides subspecies mycoides small colony. It induces significant economic losses and leads to a serious food security problem, negativel...
Autores principales: | , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952301/ https://www.ncbi.nlm.nih.gov/pubmed/33718469 http://dx.doi.org/10.3389/fvets.2021.626253 |
_version_ | 1783663698618875904 |
---|---|
author | Molla, Wassie Jemberu, Wudu Temesgen Mekonnen, Sefinew Alemu Tuli, Getachew Almaw, Gizat |
author_facet | Molla, Wassie Jemberu, Wudu Temesgen Mekonnen, Sefinew Alemu Tuli, Getachew Almaw, Gizat |
author_sort | Molla, Wassie |
collection | PubMed |
description | Contagious bovine pleuropneumonia (CBPP) is an infectious and highly contagious respiratory disease of cattle and water buffalo, which is caused by the Mycoplasma mycoides subspecies mycoides small colony. It induces significant economic losses and leads to a serious food security problem, negatively influencing peoples' livelihoods in affected countries. The disease has been reported in different parts of Ethiopia with prevalence ranging from 1.78 to 96%. However, there is not enough epidemiological information about CBPP in the northwestern part of the country, particularly in North Gondar Administrative Zone. This cross-sectional study, therefore, was conducted in four selected districts (Metema, Alefa, Quara, and Dembia) of North Gondar Administrative Zone to detect the incursion and estimate the seroprevalence of CBPP and to identify the potential predisposing factors associated with the spread and occurrence of CBPP in the area. A total of 751 serum samples were collected from 41 herds (villages) having no history of CBPP vaccination. Information like age, sex, breed, herd size, and management were collected during blood sample collection. Data related to agro-climatic zone, trade trekking route from or through CBPP endemic/epidemic zone, transhumance grazing route, vehicle route, and bordering with CBPP epidemic/endemic zone were obtained from district agricultural offices. The serum was screened for CBPP using competitive enzyme-linked immunosorbent assay (c-ELISA) test. The animal level and herd level apparent seroprevalences were 12.92% (95% CI: 10.70–15.52) and 65.85% (95% CI: 49.57–79.10), respectively. The true animal level and herd level prevalences were estimated at 20.13% (95% CI: 16.64–24.21) and 65.22% (95% CI: 48.64–78.72%), respectively. At the animal level, trekking route from or through CBPP endemic/epidemic zone to the study area [OR = 4.77 (95% CI: 1.92–11.84) compared to without trekking route] was identified as the most important risk factor for CBPP spread and seropositivity. In general, epidemiological evidence of the present study indicates that CBPP is a prevalent disease, and animal trekking is an important risk factor for spread of the disease in the study area. This needs due attention from the government and other concerned bodies for its prevention and control to mitigate its economic impact. |
format | Online Article Text |
id | pubmed-7952301 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79523012021-03-13 Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia Molla, Wassie Jemberu, Wudu Temesgen Mekonnen, Sefinew Alemu Tuli, Getachew Almaw, Gizat Front Vet Sci Veterinary Science Contagious bovine pleuropneumonia (CBPP) is an infectious and highly contagious respiratory disease of cattle and water buffalo, which is caused by the Mycoplasma mycoides subspecies mycoides small colony. It induces significant economic losses and leads to a serious food security problem, negatively influencing peoples' livelihoods in affected countries. The disease has been reported in different parts of Ethiopia with prevalence ranging from 1.78 to 96%. However, there is not enough epidemiological information about CBPP in the northwestern part of the country, particularly in North Gondar Administrative Zone. This cross-sectional study, therefore, was conducted in four selected districts (Metema, Alefa, Quara, and Dembia) of North Gondar Administrative Zone to detect the incursion and estimate the seroprevalence of CBPP and to identify the potential predisposing factors associated with the spread and occurrence of CBPP in the area. A total of 751 serum samples were collected from 41 herds (villages) having no history of CBPP vaccination. Information like age, sex, breed, herd size, and management were collected during blood sample collection. Data related to agro-climatic zone, trade trekking route from or through CBPP endemic/epidemic zone, transhumance grazing route, vehicle route, and bordering with CBPP epidemic/endemic zone were obtained from district agricultural offices. The serum was screened for CBPP using competitive enzyme-linked immunosorbent assay (c-ELISA) test. The animal level and herd level apparent seroprevalences were 12.92% (95% CI: 10.70–15.52) and 65.85% (95% CI: 49.57–79.10), respectively. The true animal level and herd level prevalences were estimated at 20.13% (95% CI: 16.64–24.21) and 65.22% (95% CI: 48.64–78.72%), respectively. At the animal level, trekking route from or through CBPP endemic/epidemic zone to the study area [OR = 4.77 (95% CI: 1.92–11.84) compared to without trekking route] was identified as the most important risk factor for CBPP spread and seropositivity. In general, epidemiological evidence of the present study indicates that CBPP is a prevalent disease, and animal trekking is an important risk factor for spread of the disease in the study area. This needs due attention from the government and other concerned bodies for its prevention and control to mitigate its economic impact. Frontiers Media S.A. 2021-02-26 /pmc/articles/PMC7952301/ /pubmed/33718469 http://dx.doi.org/10.3389/fvets.2021.626253 Text en Copyright © 2021 Molla, Jemberu, Mekonnen, Tuli and Almaw. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Veterinary Science Molla, Wassie Jemberu, Wudu Temesgen Mekonnen, Sefinew Alemu Tuli, Getachew Almaw, Gizat Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia |
title | Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia |
title_full | Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia |
title_fullStr | Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia |
title_full_unstemmed | Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia |
title_short | Seroprevalence and Risk Factors of Contagious Bovine Pleuropneumonia in Selected Districts of North Gondar Zone, Ethiopia |
title_sort | seroprevalence and risk factors of contagious bovine pleuropneumonia in selected districts of north gondar zone, ethiopia |
topic | Veterinary Science |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952301/ https://www.ncbi.nlm.nih.gov/pubmed/33718469 http://dx.doi.org/10.3389/fvets.2021.626253 |
work_keys_str_mv | AT mollawassie seroprevalenceandriskfactorsofcontagiousbovinepleuropneumoniainselecteddistrictsofnorthgondarzoneethiopia AT jemberuwudutemesgen seroprevalenceandriskfactorsofcontagiousbovinepleuropneumoniainselecteddistrictsofnorthgondarzoneethiopia AT mekonnensefinewalemu seroprevalenceandriskfactorsofcontagiousbovinepleuropneumoniainselecteddistrictsofnorthgondarzoneethiopia AT tuligetachew seroprevalenceandriskfactorsofcontagiousbovinepleuropneumoniainselecteddistrictsofnorthgondarzoneethiopia AT almawgizat seroprevalenceandriskfactorsofcontagiousbovinepleuropneumoniainselecteddistrictsofnorthgondarzoneethiopia |