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Treatment of Intestinal Inflammation With Epicutaneous Immunotherapy Requires TGF-β and IL-10 but Not Foxp3(+) Tregs
Background: Inflammatory bowel disease (IBD) involves an increase in T effector cells in the intestines that disrupts the normal balance with T regulatory cells (Tregs). A therapy that restores this balance has the potential to treat IBD. We have shown that epicutaneous exposure to OVA induces Tregs...
Autores principales: | Chen, Xin, Berin, M. Cecilia, Gillespie, Virginia L., Sampson, Hugh A., Dunkin, David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952322/ https://www.ncbi.nlm.nih.gov/pubmed/33717186 http://dx.doi.org/10.3389/fimmu.2021.637630 |
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