Cargando…

Ginsenoside Rb1 Alleviates Alcohol-Induced Liver Injury by Inhibiting Steatosis, Oxidative Stress, and Inflammation

Alcoholic liver disease (ALD) has become a heavy burden on health worldwide. Ginsenoside Rb1 (GRb1), extracted from Panax quinquefolium L., has protective effects on many diseases, but the effect and mechanisms of GRb1 on ALD remain unknown. This study aimed to investigate the protective effects of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lai, Yuqi, Tan, Qinxiang, Xv, Shu, Huang, Sha, Wang, Yuhua, Li, Yunjia, Zeng, Ting, Mo, Chan, Chen, Yuyao, Huang, Shaohui, Zhou, Chuying, Gao, Lei, Lv, Zhiping
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952325/ https://www.ncbi.nlm.nih.gov/pubmed/33716743 http://dx.doi.org/10.3389/fphar.2021.616409

Ejemplares similares

P-Hydroxyacetophenone Ameliorates Alcohol-Induced Steatosis and Oxidative Stress via the NF-κB Signaling Pathway in Zebrafish and Hepatocytes
por: Huang, Sha, et al.
Publicado: (2020)

Lupeol ameliorates LPS/D-GalN induced acute hepatic damage by suppressing inflammation and oxidative stress through TGFβ1-Nrf2 signal pathway
por: Huang, Sha, et al.
Publicado: (2021)

Hepatic TGFβr1 Deficiency Attenuates Lipopolysaccharide/D-Galactosamine–Induced Acute Liver Failure Through Inhibiting GSK3β–Nrf2–Mediated Hepatocyte Apoptosis and Ferroptosis
por: Huang, Sha, et al.
Publicado: (2022)

Neuroprotective Mechanisms of Ginsenoside Rb1 in Central Nervous System Diseases
por: Gong, Liang, et al.
Publicado: (2022)

Ginsenoside Rb2 Alleviated Atherosclerosis by Inhibiting M1 Macrophages Polarization Induced by MicroRNA-216a
por: Wang, Shuting, et al.
Publicado: (2022)

Brain Transport Profiles of Ginsenoside Rb(1) by Glucose Transporter 1: In Vitro and in Vivo
por: Wang, Yu-Zhu, et al.
Publicado: (2018)

Limonin Alleviates Non-alcoholic Fatty Liver Disease by Reducing Lipid Accumulation, Suppressing Inflammation and Oxidative Stress
por: Li, Yunjia, et al.
Publicado: (2022)

Ginsenoside Rb1 Ameliorates Diabetic Arterial Stiffening via AMPK Pathway
por: Zhang, Xinyu, et al.
Publicado: (2021)

Immunomodulatory Effect of Ginsenoside Rb2 Against Cyclophosphamide-Induced Immunosuppression in Mice
por: Zheng, Siwen, et al.
Publicado: (2022)

Modified Xiaoyaosan (MXYS) Exerts Anti-depressive Effects by Rectifying the Brain Blood Oxygen Level-Dependent fMRI Signals and Improving Hippocampal Neurogenesis in Mice
por: Gao, Lei, et al.
Publicado: (2018)

Corrigendum: Modified Xiaoyaosan (MXYS) Exerts Anti-depressive Effects by Rectifying the Brain Blood Oxygen Level-Dependent FMRI Signals and Improving Hippocampal Neurogenesis in Mice
por: Gao, Lei, et al.
Publicado: (2018)

Protective effects of ginsenosides Rg1 and Rb1 against cognitive impairment induced by simulated microgravity in rats
por: Jiang, Ning, et al.
Publicado: (2023)

Indoleamine 2,3-dioxygenase 1 limits hepatic inflammatory cells recruitment and promotes bile duct ligation-induced liver fibrosis
por: Mo, Chan, et al.
Publicado: (2021)

Ginsenoside Rb1 Produces Antidepressant-Like Effects in a Chronic Social Defeat Stress Model of Depression Through the BDNF–Trkb Signaling Pathway
por: Jiang, Ning, et al.
Publicado: (2021)

Comparison of the Protective Effects of Ginsenosides Rb1 and Rg1 on Improving Cognitive Deficits in SAMP8 Mice Based on Anti-Neuroinflammation Mechanism
por: Yang, Yujie, et al.
Publicado: (2020)

Ginsenoside Rb1 and Rd Remarkably Inhibited the Hepatic Uptake of Ophiopogonin D in Shenmai Injection Mediated by OATPs/oatps
por: Liu, Xiaopei, et al.
Publicado: (2018)

Ginsenoside Rb1 and Rb2 upregulate Akt/mTOR signaling–mediated muscular hypertrophy and myoblast differentiation
por: Go, Ga-Yeon, et al.
Publicado: (2020)

Combined Use of Emodin and Ginsenoside Rb1 Exerts Synergistic Neuroprotection in Cerebral Ischemia/Reperfusion Rats
por: Li, Yan, et al.
Publicado: (2018)

Ginsenoside Rb1 Lessens Gastric Precancerous Lesions by Interfering With β-Catenin/TCF4 Interaction
por: Zeng, Jinhao, et al.
Publicado: (2021)

RAGE promotes dysregulation of iron and lipid metabolism in alcoholic liver disease
por: Li, Yunjia, et al.
Publicado: (2022)

Ginsenoside Rb1 Enhances Atherosclerotic Plaque Stability by Improving Autophagy and Lipid Metabolism in Macrophage Foam Cells
por: Qiao, Lei, et al.
Publicado: (2017)

Ginsenoside-Rb1 for Ischemic Stroke: A Systematic Review and Meta-analysis of Preclinical Evidence and Possible Mechanisms
por: Shi, Yi-Hua, et al.
Publicado: (2020)

Protective Effects and Network Analysis of Ginsenoside Rb1 Against Cerebral Ischemia Injury: A Pharmacological Review
por: Xie, Weijie, et al.
Publicado: (2021)

Protective Effect of Patchouli Alcohol Against High-Fat Diet Induced Hepatic Steatosis by Alleviating Endoplasmic Reticulum Stress and Regulating VLDL Metabolism in Rats
por: Wu, Xue, et al.
Publicado: (2019)

Ginsenoside Rb1 Ameliorated Bavachin-Induced Renal Fibrosis via Suppressing Bip/eIF2α/CHOP Signaling-Mediated EMT
por: Ni, Yu-Hao, et al.
Publicado: (2022)

Corrigendum: Ginsenoside Rb1 Enhances Atherosclerotic Plaque Stability by Improving Autophagy and Lipid Metabolism in Macrophage Foam Cells
por: Qiao, Lei, et al.
Publicado: (2018)

Upregulation of adiponectin by Ginsenoside Rb1 contributes to amelioration of hepatic steatosis induced by high fat diet
por: Li, Yaru, et al.
Publicado: (2022)

Dapagliflozin Alleviates Hepatic Steatosis by Restoring Autophagy via the AMPK-mTOR Pathway
por: Li, Liuran, et al.
Publicado: (2021)

Anti-Inflammatory Effects of Ginsenoside Rb3 in LPS-Induced Macrophages Through Direct Inhibition of TLR4 Signaling Pathway
por: Xu, Honglin, et al.
Publicado: (2022)

Ginsenoside Rb1 improves intestinal aging via regulating the expression of sirtuins in the intestinal epithelium and modulating the gut microbiota of mice
por: Lei, Zili, et al.
Publicado: (2022)

Progress in the Conversion of Ginsenoside Rb1 into Minor Ginsenosides Using β-Glucosidases
por: Zhu, Hongrong, et al.
Publicado: (2023)

Tolerability and pharmacokinetics of ginsenosides Rb1, Rb2, Rc, Rd, and compound K after single or multiple administration of red ginseng extract in human beings
por: Choi, Min-Koo, et al.
Publicado: (2020)

Ginsenoside Rb1 Attenuates Triptolide-Induced Cytotoxicity in HL-7702 Cells via the Activation of Keap1/Nrf2/ARE Pathway
por: Peng, Hulinyue, et al.
Publicado: (2022)

Ginsenoside-Rb1-Mediated Anti-angiogenesis via Regulating PEDF and miR-33a through the Activation of PPAR-γ Pathway
por: Lu, Huixia, et al.
Publicado: (2017)

miR-203 Inhibits Alcohol-Induced Hepatic Steatosis by Targeting Lipin1
por: Cheng, Xiao-Yu, et al.
Publicado: (2018)

Alcohol Abstinence Rescues Hepatic Steatosis and Liver Injury via Improving Metabolic Reprogramming in Chronic Alcohol-Fed Mice
por: Pi, Aiwen, et al.
Publicado: (2021)

Kaempferol Alleviates Steatosis and Inflammation During Early Non-Alcoholic Steatohepatitis Associated With Liver X Receptor α-Lysophosphatidylcholine Acyltransferase 3 Signaling Pathway
por: Xiang, Hongjiao, et al.
Publicado: (2021)

Analyses of mRNA Profiling through RNA Sequencing on a SAMP8 Mouse Model in Response to Ginsenoside Rg1 and Rb1 Treatment
por: Zhang, Shuai, et al.
Publicado: (2017)

Ginsenoside Rb1 Induces Beta 3 Adrenergic Receptor–Dependent Lipolysis and Thermogenesis in 3T3-L1 Adipocytes and db/db Mice
por: Lim, Seona, et al.
Publicado: (2019)

Ginsenoside Rb1 ameliorates Glycemic Disorder in Mice With High Fat Diet-Induced Obesity via Regulating Gut Microbiota and Amino Acid Metabolism
por: Yang, Xueyuan, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_ons34t8ihq1jvdtu7j6vnvskrg