A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle

Bioactive glasses have attracted enormous attention in the field of biomaterials for dental and medical applications. Incorporation of antibacterial ions within BGs has been proved to be a promising approach to fortify their bactericidal character. In this study, homogenous BGs containing silver (Ag...

Descripción completa

Detalles Bibliográficos
Autores principales: Kazemian, Zahra, Varzandeh, Mohammad, Labbaf, Sheyda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Biomaterials Synthesis and Characterization
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952368/
https://www.ncbi.nlm.nih.gov/pubmed/33709319
http://dx.doi.org/10.1007/s10856-021-06496-9
_version_ 1783663713236025344
author Kazemian, Zahra
Varzandeh, Mohammad
Labbaf, Sheyda
author_facet Kazemian, Zahra
Varzandeh, Mohammad
Labbaf, Sheyda
author_sort Kazemian, Zahra
collection PubMed
description Bioactive glasses have attracted enormous attention in the field of biomaterials for dental and medical applications. Incorporation of antibacterial ions within BGs has been proved to be a promising approach to fortify their bactericidal character. In this study, homogenous BGs containing silver (Ag) ions were synthesized by sol–gel method. Subsequently, the presence of the embedded ions were characterized by X-ray fluorescence (XRF) elemental analysis and energy dispersive X-ray (EDX) spectroscopy. Moreover, released ions were measured in simulated body fluid (SBF) and their antibacterial effectiveness was further verified using minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) tests. A crystalline hydroxyapatite layer was formed on the Ag-BG surfaces at day 5 approved by X-ray diffraction indicating the preserved bioactivity. The resultant uniform, mono-dispersed and dense nanoparticles show 19 great potential for a range of orthopedic and dental applications. [Image: see text]
format Online
Article
Text
id pubmed-7952368
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Springer US
record_format MEDLINE/PubMed
spelling pubmed-79523682021-04-05 A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle Kazemian, Zahra Varzandeh, Mohammad Labbaf, Sheyda J Mater Sci Mater Med Biomaterials Synthesis and Characterization Bioactive glasses have attracted enormous attention in the field of biomaterials for dental and medical applications. Incorporation of antibacterial ions within BGs has been proved to be a promising approach to fortify their bactericidal character. In this study, homogenous BGs containing silver (Ag) ions were synthesized by sol–gel method. Subsequently, the presence of the embedded ions were characterized by X-ray fluorescence (XRF) elemental analysis and energy dispersive X-ray (EDX) spectroscopy. Moreover, released ions were measured in simulated body fluid (SBF) and their antibacterial effectiveness was further verified using minimum bactericidal concentration (MBC) and minimum inhibitory concentration (MIC) tests. A crystalline hydroxyapatite layer was formed on the Ag-BG surfaces at day 5 approved by X-ray diffraction indicating the preserved bioactivity. The resultant uniform, mono-dispersed and dense nanoparticles show 19 great potential for a range of orthopedic and dental applications. [Image: see text] Springer US 2021-03-12 2021 /pmc/articles/PMC7952368/ /pubmed/33709319 http://dx.doi.org/10.1007/s10856-021-06496-9 Text en © The Author(s) 2021 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Biomaterials Synthesis and Characterization
Kazemian, Zahra
Varzandeh, Mohammad
Labbaf, Sheyda
A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle
title A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle
title_full A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle
title_fullStr A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle
title_full_unstemmed A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle
title_short A facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle
title_sort facile synthesis of mono dispersed spherical silver doped bioactive glass nanoparticle
topic Biomaterials Synthesis and Characterization
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952368/
https://www.ncbi.nlm.nih.gov/pubmed/33709319
http://dx.doi.org/10.1007/s10856-021-06496-9
work_keys_str_mv AT kazemianzahra afacilesynthesisofmonodispersedsphericalsilverdopedbioactiveglassnanoparticle
AT varzandehmohammad afacilesynthesisofmonodispersedsphericalsilverdopedbioactiveglassnanoparticle
AT labbafsheyda afacilesynthesisofmonodispersedsphericalsilverdopedbioactiveglassnanoparticle
AT kazemianzahra facilesynthesisofmonodispersedsphericalsilverdopedbioactiveglassnanoparticle
AT varzandehmohammad facilesynthesisofmonodispersedsphericalsilverdopedbioactiveglassnanoparticle
AT labbafsheyda facilesynthesisofmonodispersedsphericalsilverdopedbioactiveglassnanoparticle

Ejemplares similares