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Chemical shift prediction of RNA imino groups: application toward characterizing RNA excited states

NH groups in proteins or nucleic acids are the most challenging target for chemical shift prediction. Here we show that the RNA base pair triplet motif dictates imino chemical shifts in its central base pair. A lookup table is established that links each type of base pair triplet to experimental che...

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Detalles Bibliográficos
Autores principales: Wang, Yanjiao, Han, Ge, Jiang, Xiuying, Yuwen, Tairan, Xue, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952389/
https://www.ncbi.nlm.nih.gov/pubmed/33707433
http://dx.doi.org/10.1038/s41467-021-21840-x