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Higher PGD(2) production by synovial mast cells from rheumatoid arthritis patients compared with osteoarthritis patients via miR-199a-3p/prostaglandin synthetase 2 axis

We previously reported that synovial mast cells (MCs) from patients with rheumatoid arthritis (RA) produced TNF-α in response to immune complexes via FcγRI and FcγRIIA. However, the specific functions of synovial MCs in RA remain unclear. This study aimed to elucidate those functions. Synovial tissu...

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Detalles Bibliográficos
Autores principales:	Mishima, Shintaro, Kashiwakura, Jun-ichi, Toyoshima, Shota, Sasaki-Sakamoto, Tomomi, Sano, Yutaka, Nakanishi, Kazuyoshi, Matsumoto, Kenji, Okayama, Yoshimichi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952410/ https://www.ncbi.nlm.nih.gov/pubmed/33707464 http://dx.doi.org/10.1038/s41598-021-84963-7

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