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Enteric reabsorption processes and their impact on drug pharmacokinetics

Enteric reabsorption occurs when a drug is secreted into the intestinal lumen and reabsorbed into the systemic circulation. This distribution process is evidenced by multiple peaks in pharmacokinetic profiles. Commonly, hepatobiliary drug secretion is assumed to be the underlying mechanism (enterohe...

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Detalles Bibliográficos
Autores principales: Ibarra, Manuel, Trocóniz, Iñaki F., Fagiolino, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952424/
https://www.ncbi.nlm.nih.gov/pubmed/33707635
http://dx.doi.org/10.1038/s41598-021-85174-w