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Enteric reabsorption processes and their impact on drug pharmacokinetics
Enteric reabsorption occurs when a drug is secreted into the intestinal lumen and reabsorbed into the systemic circulation. This distribution process is evidenced by multiple peaks in pharmacokinetic profiles. Commonly, hepatobiliary drug secretion is assumed to be the underlying mechanism (enterohe...
Autores principales: | Ibarra, Manuel, Trocóniz, Iñaki F., Fagiolino, Pietro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952424/ https://www.ncbi.nlm.nih.gov/pubmed/33707635 http://dx.doi.org/10.1038/s41598-021-85174-w |
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