N(6)-methyladenosine RNA modification suppresses antiviral innate sensing pathways via reshaping double-stranded RNA

Double-stranded RNA (dsRNA) is a virus-encoded signature capable of triggering intracellular Rig-like receptors (RLR) to activate antiviral signaling, but whether intercellular dsRNA structural reshaping mediated by the N(6)-methyladenosine (m(6)A) modification modulates this process remains largely...

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Detalles Bibliográficos
Autores principales: Qiu, Weinan, Zhang, Qingyang, Zhang, Rui, Lu, Yangxu, Wang, Xin, Tian, Huabin, Yang, Ying, Gu, Zijuan, Gao, Yanan, Yang, Xin, Cui, Guanshen, Sun, Baofa, Peng, Yanan, Deng, Hongyu, Peng, Hua, Yang, Angang, Yang, Yun-Gui, Yang, Pengyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952553/
https://www.ncbi.nlm.nih.gov/pubmed/33707441
http://dx.doi.org/10.1038/s41467-021-21904-y

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