Cargando…
Voltage-Gated Ca(2+) Channels in Dopaminergic Substantia Nigra Neurons: Therapeutic Targets for Neuroprotection in Parkinson's Disease?
The loss of dopamine (DA)-producing neurons in the substantia nigra pars compacta (SN) underlies the core motor symptoms of the progressive movement disorder Parkinson's disease (PD). To date, no treatment to prevent or slow SN DA neurodegeneration exists; thus, the identification of the underl...
Autor principal: | Ortner, Nadine J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952618/ https://www.ncbi.nlm.nih.gov/pubmed/33716705 http://dx.doi.org/10.3389/fnsyn.2021.636103 |
Ejemplares similares
-
Ca(2+) channels couple spiking to mitochondrial metabolism in substantia nigra dopaminergic neurons
por: Zampese, Enrico, et al.
Publicado: (2022) -
Electrical and Ca(2+) signaling in dendritic spines of substantia nigra dopaminergic neurons
por: Hage, Travis A, et al.
Publicado: (2016) -
Ca(V)1.3 L-Type Calcium Channels Increase the Vulnerability of Substantia Nigra Dopaminergic Neurons in MPTP Mouse Model of Parkinson’s Disease
por: Verma, Aditi, et al.
Publicado: (2020) -
Pedunculopontine glutamatergic neurons control spike patterning in substantia nigra dopaminergic neurons
por: Galtieri, Daniel J, et al.
Publicado: (2017) -
Activity-dependent regulation of NMDA receptors in substantia nigra dopaminergic neurones
por: Wild, Angela R, et al.
Publicado: (2014)