Cargando…
Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases
Encephalopathy has been frequently reported in patients with acute respiratory distress syndrome (ARDS) related to COVID-19, and its etiology remains undetermined. These patients display hypercatabolic state, weight loss, use of diuretics, and dialytic therapy, which represent risk factors for thiam...
Autores principales: | , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952637/ https://www.ncbi.nlm.nih.gov/pubmed/33716929 http://dx.doi.org/10.3389/fneur.2021.629273 |
_version_ | 1783663771398438912 |
---|---|
author | Branco de Oliveira, Marcus Vinicius Bernabé, Daniel Galera Irikura, Sergio Irikura, Rodrigo Batista Fontanelli, Antônio Mendes Gonçalves, Marcus Vinícius Magno |
author_facet | Branco de Oliveira, Marcus Vinicius Bernabé, Daniel Galera Irikura, Sergio Irikura, Rodrigo Batista Fontanelli, Antônio Mendes Gonçalves, Marcus Vinícius Magno |
author_sort | Branco de Oliveira, Marcus Vinicius |
collection | PubMed |
description | Encephalopathy has been frequently reported in patients with acute respiratory distress syndrome (ARDS) related to COVID-19, and its etiology remains undetermined. These patients display hypercatabolic state, weight loss, use of diuretics, and dialytic therapy, which represent risk factors for thiamine depletion. The diagnosis of Wernicke encephalopathy (WE) is challenging and based on risk factors for the depletion of thiamine. We reported three cases of patients with COVID-19-related WE treated with intravenous thiamine. All patients responded with immediate neurologic improvement, and two of them had accelerated ventilatory weaning. The cases reported suggest that thiamine deficiency could represent relevant etiology of COVID-19-related encephalopathy. |
format | Online Article Text |
id | pubmed-7952637 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-79526372021-03-13 Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases Branco de Oliveira, Marcus Vinicius Bernabé, Daniel Galera Irikura, Sergio Irikura, Rodrigo Batista Fontanelli, Antônio Mendes Gonçalves, Marcus Vinícius Magno Front Neurol Neurology Encephalopathy has been frequently reported in patients with acute respiratory distress syndrome (ARDS) related to COVID-19, and its etiology remains undetermined. These patients display hypercatabolic state, weight loss, use of diuretics, and dialytic therapy, which represent risk factors for thiamine depletion. The diagnosis of Wernicke encephalopathy (WE) is challenging and based on risk factors for the depletion of thiamine. We reported three cases of patients with COVID-19-related WE treated with intravenous thiamine. All patients responded with immediate neurologic improvement, and two of them had accelerated ventilatory weaning. The cases reported suggest that thiamine deficiency could represent relevant etiology of COVID-19-related encephalopathy. Frontiers Media S.A. 2021-02-26 /pmc/articles/PMC7952637/ /pubmed/33716929 http://dx.doi.org/10.3389/fneur.2021.629273 Text en Copyright © 2021 Branco de Oliveira, Bernabé, Irikura, Irikura, Fontanelli and Gonçalves. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Neurology Branco de Oliveira, Marcus Vinicius Bernabé, Daniel Galera Irikura, Sergio Irikura, Rodrigo Batista Fontanelli, Antônio Mendes Gonçalves, Marcus Vinícius Magno Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases |
title | Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases |
title_full | Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases |
title_fullStr | Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases |
title_full_unstemmed | Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases |
title_short | Wernicke Encephalopathy in COVID-19 Patients: Report of Three Cases |
title_sort | wernicke encephalopathy in covid-19 patients: report of three cases |
topic | Neurology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952637/ https://www.ncbi.nlm.nih.gov/pubmed/33716929 http://dx.doi.org/10.3389/fneur.2021.629273 |
work_keys_str_mv | AT brancodeoliveiramarcusvinicius wernickeencephalopathyincovid19patientsreportofthreecases AT bernabedanielgalera wernickeencephalopathyincovid19patientsreportofthreecases AT irikurasergio wernickeencephalopathyincovid19patientsreportofthreecases AT irikurarodrigobatista wernickeencephalopathyincovid19patientsreportofthreecases AT fontanelliantoniomendes wernickeencephalopathyincovid19patientsreportofthreecases AT goncalvesmarcusviniciusmagno wernickeencephalopathyincovid19patientsreportofthreecases |