Cargando…
Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation
BACKGROUNDS/AIMS: Biliary complications continue to be the major morbidity and mortality causes following living donor liver transplantation (LT). Endoscopic retrograde cholangiopancreatography (ERCP) has been performed to identify the biliary leakage source. However, this can lead to retrograde cho...
Autores principales: | , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Korean Association of Hepato-Biliary-Pancreatic Surgery
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952671/ https://www.ncbi.nlm.nih.gov/pubmed/33649253 http://dx.doi.org/10.14701/ahbps.2021.25.1.39 |
_version_ | 1783663779533291520 |
---|---|
author | Lim, Chang Jin Hong, Kwangpyo Lee, Jeong-Moo Han, Eui Soo Hong, Suk Kyun Choi, YoungRok Yi, Nam-Joon Lee, Kwang-Woong Suh, Kyung-Suk |
author_facet | Lim, Chang Jin Hong, Kwangpyo Lee, Jeong-Moo Han, Eui Soo Hong, Suk Kyun Choi, YoungRok Yi, Nam-Joon Lee, Kwang-Woong Suh, Kyung-Suk |
author_sort | Lim, Chang Jin |
collection | PubMed |
description | BACKGROUNDS/AIMS: Biliary complications continue to be the major morbidity and mortality causes following living donor liver transplantation (LT). Endoscopic retrograde cholangiopancreatography (ERCP) has been performed to identify the biliary leakage source. However, this can lead to retrograde cholangitis and pancreatitis, and is not sufficient to diagnose bile leakage from cuts’ surface. This study aimed to describe the use of T1-Weighted Magnetic Resonance (MR) Cholangiography with Gd-EOB-DTPA (Primovist) examination for evaluating the bile duct complication following LT. METHODS: From March 2012 to December 2018, 869 adult LT were performed at the Seoul National University Hospital. Forty-three recipients had undergone MR Cholangiography with Gd-EOB-DTPA. We reviewed these cases with their clinical outcomes and described the utility of the MR cholangiography with Gd-EOB-DTPA. RESULTS: In radiologic examinations performed in the patients suspected of bile duct complication, 95% had bile leakage and stricture. Cut surface leakage was diagnosed in two cases, and biliary leakage from the anastomosis site was diagnosed in the others. Most patients with leakage had undergone percutaneous drainage and ERCP, which was performed to evaluate the bile secretion function of the hepatocytes. There was no contrast-enhanced bile duct image in one case with severe rejection, and it might have been related to hepatocyte secretary dysfunction. CONCLUSIONS: T1-Weighted MR Cholangiography with Gd-EOB-DTPA 40-minute delay examination is a feasible and safe non-invasive procedure for identifying biliary leakage sites. |
format | Online Article Text |
id | pubmed-7952671 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | The Korean Association of Hepato-Biliary-Pancreatic Surgery |
record_format | MEDLINE/PubMed |
spelling | pubmed-79526712021-03-26 Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation Lim, Chang Jin Hong, Kwangpyo Lee, Jeong-Moo Han, Eui Soo Hong, Suk Kyun Choi, YoungRok Yi, Nam-Joon Lee, Kwang-Woong Suh, Kyung-Suk Ann Hepatobiliary Pancreat Surg Original Article BACKGROUNDS/AIMS: Biliary complications continue to be the major morbidity and mortality causes following living donor liver transplantation (LT). Endoscopic retrograde cholangiopancreatography (ERCP) has been performed to identify the biliary leakage source. However, this can lead to retrograde cholangitis and pancreatitis, and is not sufficient to diagnose bile leakage from cuts’ surface. This study aimed to describe the use of T1-Weighted Magnetic Resonance (MR) Cholangiography with Gd-EOB-DTPA (Primovist) examination for evaluating the bile duct complication following LT. METHODS: From March 2012 to December 2018, 869 adult LT were performed at the Seoul National University Hospital. Forty-three recipients had undergone MR Cholangiography with Gd-EOB-DTPA. We reviewed these cases with their clinical outcomes and described the utility of the MR cholangiography with Gd-EOB-DTPA. RESULTS: In radiologic examinations performed in the patients suspected of bile duct complication, 95% had bile leakage and stricture. Cut surface leakage was diagnosed in two cases, and biliary leakage from the anastomosis site was diagnosed in the others. Most patients with leakage had undergone percutaneous drainage and ERCP, which was performed to evaluate the bile secretion function of the hepatocytes. There was no contrast-enhanced bile duct image in one case with severe rejection, and it might have been related to hepatocyte secretary dysfunction. CONCLUSIONS: T1-Weighted MR Cholangiography with Gd-EOB-DTPA 40-minute delay examination is a feasible and safe non-invasive procedure for identifying biliary leakage sites. The Korean Association of Hepato-Biliary-Pancreatic Surgery 2021-02-28 2021-02-28 /pmc/articles/PMC7952671/ /pubmed/33649253 http://dx.doi.org/10.14701/ahbps.2021.25.1.39 Text en Copyright © 2021 by The Korean Association of Hepato-Biliary-Pancreatic Surgery This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Lim, Chang Jin Hong, Kwangpyo Lee, Jeong-Moo Han, Eui Soo Hong, Suk Kyun Choi, YoungRok Yi, Nam-Joon Lee, Kwang-Woong Suh, Kyung-Suk Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation |
title | Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation |
title_full | Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation |
title_fullStr | Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation |
title_full_unstemmed | Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation |
title_short | Clinical usefulness of T1-weighted MR cholangiography with Gd-EOB-DTPA for the evaluation of biliary complication after liver transplantation |
title_sort | clinical usefulness of t1-weighted mr cholangiography with gd-eob-dtpa for the evaluation of biliary complication after liver transplantation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952671/ https://www.ncbi.nlm.nih.gov/pubmed/33649253 http://dx.doi.org/10.14701/ahbps.2021.25.1.39 |
work_keys_str_mv | AT limchangjin clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT hongkwangpyo clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT leejeongmoo clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT haneuisoo clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT hongsukkyun clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT choiyoungrok clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT yinamjoon clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT leekwangwoong clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation AT suhkyungsuk clinicalusefulnessoft1weightedmrcholangiographywithgdeobdtpafortheevaluationofbiliarycomplicationafterlivertransplantation |