MAGI1 inhibits the AMOTL2/p38 stress pathway and prevents luminal breast tumorigenesis

Alterations to cell polarization or to intercellular junctions are often associated with epithelial cancer progression, including breast cancers (BCa). We show here that the loss of the junctional scaffold protein MAGI1 is associated with bad prognosis in luminal BCa, and promotes tumorigenesis. E-c...

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Detalles Bibliográficos
Autores principales: Kantar, Diala, Mur, Emilie Bousquet, Mancini, Maicol, Slaninova, Vera, Salah, Yezza Ben, Costa, Luca, Forest, Elodie, Lassus, Patrice, Géminard, Charles, Boissière-Michot, Florence, Orsetti, Béatrice, Theillet, Charles, Colinge, Jacques, Benistant, Christine, Maraver, Antonio, Heron-Milhavet, Lisa, Djiane, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952706/
https://www.ncbi.nlm.nih.gov/pubmed/33707576
http://dx.doi.org/10.1038/s41598-021-85056-1

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