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Multi-Electrode Array Analysis Identifies Complex Dopamine Responses and Glucose Sensing Properties of Substantia Nigra Neurons in Mouse Brain Slices

Dopaminergic (DA) midbrain neurons within the substantia nigra (SN) display an autonomous pacemaker activity that is crucial for dopamine release and voluntary movement control. Their progressive degeneration is a hallmark of Parkinson's disease. Their metabolically demanding activity-mode affe...

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Detalles Bibliográficos
Autores principales: Mannal, Nadja, Kleiner, Katharina, Fauler, Michael, Dougalis, Antonios, Poetschke, Christina, Liss, Birgit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952765/
https://www.ncbi.nlm.nih.gov/pubmed/33716704
http://dx.doi.org/10.3389/fnsyn.2021.635050