Cargando…

Preoperative predictors of restoration in quality of life after surgery for lung cancer

BACKGROUND: The preoperative predictors of quality of life (QOL) in patients who undergo lung resection for lung cancer are poorly known. Here, we investigated these predictors in such patients using two QOL measures. METHODS: In this single‐institutional prospective cohort study, we administered th...

Descripción completa

Detalles Bibliográficos
Autores principales: Ichimura, Hideo, Kobayashi, Keisuke, Gosho, Masahiko, Nakaoka, Kojiro, Yanagihara, Takahiro, Ueda, Sho, Saeki, Yusuke, Maki, Naoki, Kobayashi, Naohiro, Kikuchi, Shinji, Suzuki, Hisashi, Goto, Yukinobu, Sato, Yukio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952797/
https://www.ncbi.nlm.nih.gov/pubmed/33508893
http://dx.doi.org/10.1111/1759-7714.13819
_version_ 1783663809073774592
author Ichimura, Hideo
Kobayashi, Keisuke
Gosho, Masahiko
Nakaoka, Kojiro
Yanagihara, Takahiro
Ueda, Sho
Saeki, Yusuke
Maki, Naoki
Kobayashi, Naohiro
Kikuchi, Shinji
Suzuki, Hisashi
Goto, Yukinobu
Sato, Yukio
author_facet Ichimura, Hideo
Kobayashi, Keisuke
Gosho, Masahiko
Nakaoka, Kojiro
Yanagihara, Takahiro
Ueda, Sho
Saeki, Yusuke
Maki, Naoki
Kobayashi, Naohiro
Kikuchi, Shinji
Suzuki, Hisashi
Goto, Yukinobu
Sato, Yukio
author_sort Ichimura, Hideo
collection PubMed
description BACKGROUND: The preoperative predictors of quality of life (QOL) in patients who undergo lung resection for lung cancer are poorly known. Here, we investigated these predictors in such patients using two QOL measures. METHODS: In this single‐institutional prospective cohort study, we administered the EQ‐5D‐5 levels (EQ‐5D‐5L) from January 2015, and the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire with 30 items from April 2015 to April 2018 preoperatively (Pre) and at one month postoperatively (M1), and one year postoperatively (Y1). General health status was measured by the EQ‐5D visual analogue scale (VAS) and EORTC global health status/QOL (GHS) scores. Multivariable linear regression analyses were used to explore the preoperative predictors of QOL at Y1. RESULTS: A total of 223 patients were included in the study. The EQ‐5D VAS and EORTC GHS scores, at Pre, M1, and Y1, were 80 ± 15, 77 ± 15, and 84 ± 11; and 74 ± 19, 65 ± 20, and 78 ± 17, respectively. In the multivariable analyses, the albumin level, preoperative VAS score, and preoperative pain/discomfort and anxiety/depression were identified as predictors by the EQ‐5D VAS score. The preoperative EORTC GHS score, absence of diabetes mellitus, preoperative cognitive function score, and preoperative symptom score of pain were identified as predictors by the EORTC GHS score. CONCLUSIONS: The EQ‐5D VAS and EORTC GHS scores traced similar trajectories of QOL. In both QOL measures, preoperative pain was found as a common predictor. These predictors may help improve patient/survivor care in the future.
format Online
Article
Text
id pubmed-7952797
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher John Wiley & Sons Australia, Ltd
record_format MEDLINE/PubMed
spelling pubmed-79527972021-03-17 Preoperative predictors of restoration in quality of life after surgery for lung cancer Ichimura, Hideo Kobayashi, Keisuke Gosho, Masahiko Nakaoka, Kojiro Yanagihara, Takahiro Ueda, Sho Saeki, Yusuke Maki, Naoki Kobayashi, Naohiro Kikuchi, Shinji Suzuki, Hisashi Goto, Yukinobu Sato, Yukio Thorac Cancer Original Articles BACKGROUND: The preoperative predictors of quality of life (QOL) in patients who undergo lung resection for lung cancer are poorly known. Here, we investigated these predictors in such patients using two QOL measures. METHODS: In this single‐institutional prospective cohort study, we administered the EQ‐5D‐5 levels (EQ‐5D‐5L) from January 2015, and the European Organization for Research and Treatment of Cancer (EORTC) Quality of Life Questionnaire with 30 items from April 2015 to April 2018 preoperatively (Pre) and at one month postoperatively (M1), and one year postoperatively (Y1). General health status was measured by the EQ‐5D visual analogue scale (VAS) and EORTC global health status/QOL (GHS) scores. Multivariable linear regression analyses were used to explore the preoperative predictors of QOL at Y1. RESULTS: A total of 223 patients were included in the study. The EQ‐5D VAS and EORTC GHS scores, at Pre, M1, and Y1, were 80 ± 15, 77 ± 15, and 84 ± 11; and 74 ± 19, 65 ± 20, and 78 ± 17, respectively. In the multivariable analyses, the albumin level, preoperative VAS score, and preoperative pain/discomfort and anxiety/depression were identified as predictors by the EQ‐5D VAS score. The preoperative EORTC GHS score, absence of diabetes mellitus, preoperative cognitive function score, and preoperative symptom score of pain were identified as predictors by the EORTC GHS score. CONCLUSIONS: The EQ‐5D VAS and EORTC GHS scores traced similar trajectories of QOL. In both QOL measures, preoperative pain was found as a common predictor. These predictors may help improve patient/survivor care in the future. John Wiley & Sons Australia, Ltd 2021-01-28 2021-03 /pmc/articles/PMC7952797/ /pubmed/33508893 http://dx.doi.org/10.1111/1759-7714.13819 Text en © 2021 The Authors. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd This is an open access article under the terms of the http://creativecommons.org/licenses/by-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited and no modifications or adaptations are made.
spellingShingle Original Articles
Ichimura, Hideo
Kobayashi, Keisuke
Gosho, Masahiko
Nakaoka, Kojiro
Yanagihara, Takahiro
Ueda, Sho
Saeki, Yusuke
Maki, Naoki
Kobayashi, Naohiro
Kikuchi, Shinji
Suzuki, Hisashi
Goto, Yukinobu
Sato, Yukio
Preoperative predictors of restoration in quality of life after surgery for lung cancer
title Preoperative predictors of restoration in quality of life after surgery for lung cancer
title_full Preoperative predictors of restoration in quality of life after surgery for lung cancer
title_fullStr Preoperative predictors of restoration in quality of life after surgery for lung cancer
title_full_unstemmed Preoperative predictors of restoration in quality of life after surgery for lung cancer
title_short Preoperative predictors of restoration in quality of life after surgery for lung cancer
title_sort preoperative predictors of restoration in quality of life after surgery for lung cancer
topic Original Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952797/
https://www.ncbi.nlm.nih.gov/pubmed/33508893
http://dx.doi.org/10.1111/1759-7714.13819
work_keys_str_mv AT ichimurahideo preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT kobayashikeisuke preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT goshomasahiko preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT nakaokakojiro preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT yanagiharatakahiro preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT uedasho preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT saekiyusuke preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT makinaoki preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT kobayashinaohiro preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT kikuchishinji preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT suzukihisashi preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT gotoyukinobu preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer
AT satoyukio preoperativepredictorsofrestorationinqualityoflifeaftersurgeryforlungcancer