Cargando…

Bat and pangolin coronavirus spike glycoprotein structures provide insights into SARS-CoV-2 evolution

In recognizing the host cellular receptor and mediating fusion of virus and cell membranes, the spike (S) glycoprotein of coronaviruses is the most critical viral protein for cross-species transmission and infection. Here we determined the cryo-EM structures of the spikes from bat (RaTG13) and pango...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shuyuan, Qiao, Shuyuan, Yu, Jinfang, Zeng, Jianwei, Shan, Sisi, Tian, Long, Lan, Jun, Zhang, Linqi, Wang, Xinquan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7952905/ https://www.ncbi.nlm.nih.gov/pubmed/33707453 http://dx.doi.org/10.1038/s41467-021-21767-3

Ejemplares similares

Cryo-EM structures of HKU2 and SADS-CoV spike glycoproteins provide insights into coronavirus evolution
por: Yu, Jinfang, et al.
Publicado: (2020)

The spike glycoprotein of highly pathogenic human coronaviruses: structural insights for understanding infection, evolution and inhibition
por: Qiao, Shuyuan, et al.
Publicado: (2022)

Cryoelectron microscopy structures of a human neutralizing antibody bound to MERS-CoV spike glycoprotein
por: Zhang, Shuyuan, et al.
Publicado: (2022)

Crystallization and Structural Determination of the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
por: Zhou, Haixia, et al.
Publicado: (2019)

Structural definition of a neutralization epitope on the N-terminal domain of MERS-CoV spike glycoprotein
por: Zhou, Haixia, et al.
Publicado: (2019)

Immunogenicity of the spike glycoprotein of Bat SARS-like coronavirus
por: Hou, Yu-xuan, et al.
Publicado: (2010)

Structure and binding properties of Pangolin-CoV spike glycoprotein inform the evolution of SARS-CoV-2
por: Wrobel, Antoni G., et al.
Publicado: (2021)

Functional comparison of SARS-CoV-2 with closely related pangolin and bat coronaviruses
por: Nie, Jianhui, et al.
Publicado: (2021)

Characterisation of B.1.1.7 and Pangolin coronavirus spike provides insights on the evolutionary trajectory of SARS-CoV-2.
por: Dicken, Samuel J., et al.
Publicado: (2021)

Strategy To Assess Zoonotic Potential Reveals Low Risk Posed by SARS-Related Coronaviruses from Bat and Pangolin
por: Yang, Yong, et al.
Publicado: (2023)

Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia
por: Wacharapluesadee, Supaporn, et al.
Publicado: (2021)

From bats to pangolins: new insights into species differences in the structure and function of the immune system
por: Haley, Patrick J.
Publicado: (2022)

Loss of Spike N370 glycosylation as an important evolutionary event for the enhanced infectivity of SARS-CoV-2
por: Zhang, Shuyuan, et al.
Publicado: (2022)

Computational Analysis of SARS-CoV-2 and SARS-Like Coronavirus Diversity in Human, Bat and Pangolin Populations
por: Dimonaco, Nicholas J., et al.
Publicado: (2020)

Author Correction: Evidence for SARS-CoV-2 related coronaviruses circulating in bats and pangolins in Southeast Asia
por: Wacharapluesadee, Supaporn, et al.
Publicado: (2021)

Comparative genomic signature representations of the emerging COVID-19 coronavirus and other coronaviruses: High identity and possible recombination between Bat and Pangolin coronaviruses
por: Touati, Rabeb, et al.
Publicado: (2020)

Comparative analysis of single cell lung atlas of bat, cat, tiger, and pangolin
por: Wang, Xiran, et al.
Publicado: (2022)

A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry
por: Chen, Jing, et al.
Publicado: (2023)

The use of SARS-CoV-2-related coronaviruses from bats and pangolins to polarize mutations in SARS-Cov-2
por: Li, Tao, et al.
Publicado: (2020)

Pangolins and bats living together in underground burrows in Lopé National Park, Gabon
por: Lehmann, David, et al.
Publicado: (2020)

The species coalescent indicates possible bat and pangolin origins of the COVID-19 pandemic
por: Yang, Jialin, et al.
Publicado: (2023)

Whole-genome resequencing of Chinese pangolins reveals a population structure and provides insights into their conservation
por: Wang, Qing, et al.
Publicado: (2022)

Pangolin genomes and the evolution of mammalian scales and immunity
por: Choo, Siew Woh, et al.
Publicado: (2016)

Cross-Neutralization of SARS-CoV-2-Specific Antibodies in Convalescent and Immunized Human Sera against the Bat and Pangolin Coronaviruses
por: Srisutthisamphan, Kanjana, et al.
Publicado: (2022)

Cryo-EM structure of the SARS coronavirus spike glycoprotein in complex with its host cell receptor ACE2
por: Song, Wenfei, et al.
Publicado: (2018)

Host range, transmissibility and antigenicity of a pangolin coronavirus
por: Hou, Yixuan J., et al.
Publicado: (2023)

Bats, pangolins, minks and other animals - villains or victims of SARS-CoV-2?
por: do Vale, Beatriz, et al.
Publicado: (2021)

Identification of Diverse Bat Alphacoronaviruses and Betacoronaviruses in China Provides New Insights Into the Evolution and Origin of Coronavirus-Related Diseases
por: Han, Yelin, et al.
Publicado: (2019)

A Potent and Protective Human Neutralizing Antibody Against SARS-CoV-2 Variants
por: Shan, Sisi, et al.
Publicado: (2021)

Incorporation of Spike and Membrane Glycoproteins into Coronavirus Virions
por: Ujike, Makoto, et al.
Publicado: (2015)

Spike Glycoprotein-Mediated Entry of SARS Coronaviruses
por: Wang, Lin, et al.
Publicado: (2020)

Proteolysis of Sars-Associated Coronavirus Spike Glycoprotein
por: Simmons, Graham, et al.
Publicado: (2006)

Corrigendum: Identification of Diverse Bat Alphacoronaviruses and Betacoronaviruses in China Provides New Insights Into the Evolution and Origin of Coronavirus-Related Diseases
por: Han, Yelin, et al.
Publicado: (2020)

Molecular simulation studies of the interactions between the human/pangolin/cat/bat ACE2 and the receptor binding domain of the SARS-CoV-2 spike protein
por: Ma, Shaojie, et al.
Publicado: (2021)

Pangolins Harbor SARS-CoV-2-Related Coronaviruses
por: Han, Guan-Zhu
Publicado: (2020)

Structural Definition of a Unique Neutralization Epitope on the Receptor-Binding Domain of MERS-CoV Spike Glycoprotein
por: Zhang, Senyan, et al.
Publicado: (2018)

Single intranasal immunization with chimpanzee adenovirus-based vaccine induces sustained and protective immunity against MERS-CoV infection
por: Jia, Wenxu, et al.
Publicado: (2019)

Genetic drift of human coronavirus OC43 spike gene during adaptive evolution
por: Ren, Lili, et al.
Publicado: (2015)

Potential Therapeutic Targeting of Coronavirus Spike Glycoprotein Priming
por: Barile, Elisa, et al.
Publicado: (2020)

Closing coronavirus spike glycoproteins by structure-guided design
por: McCallum, Matthew, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_0gjfuagjcb2uvrrm4kfjbprbj1